2025

Bachmann KF, Asrani VM, Reintam Blaser A. Assessing gastrointestinal system dysfunction in intensive care. Curr Opin Crit Care. 2025;31(2):172-178. https://doi.org/10.1097/MCC.0000000000001248

Bachmann KF, Cotoia A, Reintam Blaser A. Gastrointestinal function and nutritional interventions in septic shock. Curr Opin Crit Care. 2025;31(5):599-607. https://doi.org/10.1097/MCC.0000000000001302

Jian Z, Liu X, Kouz K, Settels JJ, Davies S, Scheeren TWL et al. Deep learning model to identify and validate hypotension endotypes in surgical and critically ill patients. Br J Anaesth. 2025;134(2):308-316. https://doi.org/10.1016/j.bja.2024.10.048

Prazak J, Schenk NV, Schefold JC, Bachmann KF, Berger D. Effects of Preoxygenation With Intratracheal Suctioning During Extubation: An Alternating Cluster-Controlled Trial (INtratracheal suctioning and oxygenation AT Extubation [INNOVATE]). Crit Care Med. 2025;53(11):e2179-e2190. https://doi.org/10.1097/CCM.0000000000006819

Reintam Blaser A, Davies T, Bachmann KF. Core outcome sets and trials of nutrition and metabolism interventions. Curr Opin Clin Nutr Metab Care. 2025;29(2):159-168. https://doi.org/10.1097/MCO.0000000000001191

2024

Bachmann KF, Haenggi M, Jakob SM, Takala J, Gattinoni L, Berger D. Comment on: "A novel 'shunt fraction' method to derive native cardiac output during liberation from central VA ECMO" by Lim, HS. ESC Heart Fail. 2024;11(4):2464-2466. https://doi.org/10.1002/ehf2.14804

Bachmann KF, Jenkins B, Asrani V, Bear DE, Bolondi G, Boraso S et al. Core outcome set of daily monitoring of gastrointestinal function in adult critically ill patients: a modified Delphi consensus process (COSMOGI). Crit Care. 2024;28(1):420. https://doi.org/10.1186/s13054-024-05192-8

Bachmann KF, Moller PW, Hunziker L, Maggiorini M, Berger D. Mechanisms maintaining right ventricular contractility-to-pulmonary arterial elastance ratio in VA ECMO: a retrospective animal data analysis of RV-PA coupling. J Intensive Care. 2024;12(1):19. https://doi.org/10.1186/s40560-024-00730-6

Berger D, Stanger EJ, Jenni H, Fried PD, Bachmann KF. Modified Thermodilution for Simultaneous Cardiac Output and Recirculation Assessment in Veno-venous Extracorporeal Membrane Oxygenation: A Prospective Diagnostic Accuracy Study. Anesthesiology. 2024;140(5):1002-1015. https://doi.org/10.1097/ALN.0000000000004895

Iten M, Gschwend C, Ostini A, Cameron DR, Goepfert C, Berger D et al. BET-inhibitor DYB-41 reduces pulmonary inflammation and local and systemic cytokine levels in LPS-induced acute respiratory distress syndrome: an experimental rodent study. Intensive Care Med Exp. 2024;12(1):19. https://doi.org/10.1186/s40635-024-00604-z

Levis A, Gardill M, Bachmann KF, Berger D, Schandl C, Piquilloud L et al. Bilateral phrenic nerve block to reduce hazardous respiratory drive in a mechanically ventilated patient with COVID-19-A case report. Clin Case Rep. 2024;12(5):e8850. https://doi.org/10.1002/ccr3.8850

Petrucci M, Spadavecchia C, Bachmann KF, Berger D, Mirra A, Casoni D. The nociceptive withdrawal reflex during spinal analgesia in pigs undergoing veno-arterial extracorporeal membrane oxygenation: a prospective observational study. Front Vet Sci. 2024;11:1449297. https://doi.org/10.3389/fvets.2024.1449297

Pölkki A, Pekkarinen PT, Hess B, Blaser AR, Bachmann KF, Lakbar I et al. Noradrenaline dose cutoffs to characterise the severity of cardiovascular failure: Data-based development and external validation. Acta Anaesthesiol Scand. 2024;68(10):1400-1408. https://doi.org/10.1111/aas.14519

Reintam Blaser A, Cotoia A, Berger MM, Padar M, Arabi YM, Casaer MP et al. How to define parenteral nutrition. Crit Care. 2024;28(1):372. https://doi.org/10.1186/s13054-024-05153-1

2023

Bachmann KF, Berger D, Moller PW. Interactions between extracorporeal support and the cardiopulmonary system. Front Physiol. 2023;14:1231016. https://doi.org/10.3389/fphys.2023.1231016

Berger D, Werner Moller P, Bachmann KF. Cardiopulmonary interactions-which monitoring tools to use?. Front Physiol. 2023;14:1234915. https://doi.org/10.3389/fphys.2023.1234915

Messmer A, Pietsch U, Siegemund M, Buehler P, Waskowski J, Müller M et al. Protocolised early de-resuscitation in septic shock (REDUCE): protocol for a randomised controlled multicentre feasibility trial. BMJ Open. 2023;13(9):e074847. https://doi.org/10.1136/bmjopen-2023-074847

Moller PW, Berger DC. Commentary: Feasibility to estimate mean systemic filling pressure with inspiratory holds at the bedside. Front Physiol. 2023;14:1135769. https://doi.org/10.3389/fphys.2023.1135769

Reintam Blaser A, Bachmann KF, Deane AM. Gastrointestinal function in critically ill patients. Curr Opin Clin Nutr Metab Care. 2023;26(5):463-469. https://doi.org/10.1097/MCO.0000000000000955

Stanger EJ, Berger DC, Jenni H, Bachmann KF. Behaviour and stability of thermodilution signals in a closed extracorporeal circuit: a bench study. J Clin Monit Comput. 2023;37(4):1095-1102. https://doi.org/10.1007/s10877-023-01018-0

2022

Berger D, Wigger O, Bachmann KF, Bloechlinger S. Reply to La Via and colleagues. Clin Res Cardiol. 2022;112(5):702. https://doi.org/10.1007/s00392-022-02062-7

Berger D, Wigger O, de Marchi S, Grübler MR, Bloch A, Kurmann R et al. The effects of positive end-expiratory pressure on cardiac function: a comparative echocardiography-conductance catheter study. Clin Res Cardiol. 2022;111(6):705-719. https://doi.org/10.1007/s00392-022-02014-1

Berger DC, Zwicker L, Nettelbeck K, Casoni D, Heinisch PP, Jenni H et al. Integral assessment of gas exchange during veno-arterial ECMO: accuracy and precision of a modified Fick principle in a porcine model. Am J Physiol Lung Cell Mol Physiol. 2022;324(2):L102-L113. https://doi.org/10.1152/ajplung.00045.2022

Heliste M, Pettilä V, Berger D, Jakob SM, Wilkman E. Beta-blocker treatment in the critically ill: a systematic review and meta-analysis. Ann Med. 2022;54(1):1994-2010. https://doi.org/10.1080/07853890.2022.2098376

Werner-Moller P, Heinisch PP, Hana A, Bachmann KF, Sondergaard S, Jakob SM et al. Experimental validation of a mean systemic pressure analog against zero-flow measurements in porcine VA-ECMO. J Appl Physiol (1985). 2022;132(3):726-736. https://doi.org/10.1152/japplphysiol.00804.2021

2021

Bachmann KF, Vasireddy R, Heinisch PP, Jenni H, Vogt A, Berger D. Estimating cardiac output based on gas exchange during veno-arterial extracorporeal membrane oxygenation in a simulation study using paediatric oxygenators. Sci Rep. 2021;11(1):11528. https://doi.org/10.1038/s41598-021-90747-w

Berger-Estilita J, Haenggi M, Ott D, Berger D. Accuracy of the end-expiratory lung volume measured by the modified nitrogen washout/washin technique: a bench study. J Transl Med. 2021;19(1):36. https://doi.org/10.1186/s12967-021-02703-x

Kuhn KF, Grunow JJ, Leimer P, Lorenz M, Berger D, Schefold JC et al. Assessment of magnetic flux density properties of electromagnetic noninvasive phrenic nerve stimulations for environmental safety in an ICU environment. Sci Rep. 2021;11(1):16317. https://doi.org/10.1038/s41598-021-95489-3

Valenti E, Moller PW, Takala J, Berger D. Collapsibility of caval vessels and right ventricular afterload: decoupling of stroke volume variation from preload during mechanical ventilation. J Appl Physiol (1985). 2021;130(5):1562-1572. https://doi.org/10.1152/japplphysiol.01039.2020

2020

Bachmann KF, Berger D. Impaired membrane lung COelimination: is it dead space, V/Q ratio or acidosis?. Perfusion. 2020;35(8):875-877. https://doi.org/10.1177/0267659120947379

Bachmann KF, Haenggi M, Jakob SM, Takala J, Gattinoni L, Berger D. Gas exchange calculation may estimate changes in pulmonary blood flow during veno-arterial extracorporeal membrane oxygenation in a porcine model. Am J Physiol Lung Cell Mol Physiol. 2020;318(6):L1211-L1221. https://doi.org/10.1152/ajplung.00167.2019

Bachmann KF, Zwicker L, Nettelbeck K, Casoni D, Heinisch PP, Jenni H et al. Assessment of Right Heart Function during Extracorporeal Therapy by Modified Thermodilution in a Porcine Model. Anesthesiology. 2020;133(4):879-891. https://doi.org/10.1097/ALN.0000000000003443

Berger D, Hobi J, Möller PW, Haenggi M, Takala J, Jakob SM. Right ventricular stroke volume assessed by pulmonary artery pulse contour analysis. Intensive Care Med Exp. 2020;8(1):58. https://doi.org/10.1186/s40635-020-00347-7

Liu S, Moller PW, Kohler A, Hana A, Beldi G, Obrist D et al. Effects of Trendelenburg position and increased airway pressure on hepatic regional blood flow of normal and resected liver. J Appl Physiol (1985). 2020;128(3):667-680. https://doi.org/10.1152/japplphysiol.00705.2019

Liu S, do Amaral Campos PPZ, Casoni D, Berger D, Kohler A, Bloch A et al. Defense mechanisms to increasing back pressure for hepatic oxygen transport and venous return in porcine fecal peritonitis. Am J Physiol Gastrointest Liver Physiol. 2020;319(3):G289-G302. https://doi.org/10.1152/ajpgi.00216.2020

Mosbahi S, Heinisch PP, Schoenhoff FS, Berger DC. COVID-19-associated aortic arch thrombus. Eur J Cardiothorac Surg. 2020;58(4):870. https://doi.org/10.1093/ejcts/ezaa304

Sweda R, Berger D, Heverhagen JT, Hunziker L. Pulmonary haemorrhage on veno-arterial ECMO: consequences of missed aortic valve regurgitation. Eur Heart J. 2020;41(47):4530. https://doi.org/10.1093/eurheartj/ehaa825

Werner-Moller P, Berger D, Takala J. Letter to the Editor: Venous return and the physical connection between distribution of segmental pressures and volumes. Am J Physiol Heart Circ Physiol. 2020;318(1):H203-H204. https://doi.org/10.1152/ajpheart.00698.2019

Zante B, Berger DC, Schefold JC, Bachmann KF. Dissociation of Arterial Oxygen Saturation and Oxygen Delivery in VV-ECMO: The Trend Is Your Friend. J Cardiothorac Vasc Anesth. 2020;35(3):962-963. https://doi.org/10.1053/j.jvca.2020.06.084

Zuercher P, Schenk NV, Moret C, Berger D, Abegglen R, Schefold JC. Risk Factors for Dysphagia in ICU Patients After Invasive Mechanical Ventilation. Chest. 2020;158(5):1983-1991. https://doi.org/10.1016/j.chest.2020.05.576

2019

Berger D, Moller PW, Takala J. Reply to "Is the Guytonian framework justified in explaining heart lung interactions?" and "Venous return, mean systemic pressure and getting the right answer for the wrong reason". Ann Transl Med. 2019;7(8):186. https://doi.org/10.21037/atm.2019.04.50

Merz TM, Cioccari L, Frey PM, Bloch A, Berger D, Zante B et al. Continual hemodynamic monitoring with a single-use transesophageal echocardiography probe in critically ill patients with shock: a randomized controlled clinical trial. Intensive Care Med. 2019;45(8):1093-1102. https://doi.org/10.1007/s00134-019-05670-6

Moller PW, Hana A, Heinisch PP, Liu S, Djafarzadeh S, Haenggi M et al. The Effects of Vasoconstriction And Volume Expansion on Veno-Arterial ECMO Flow. Shock. 2019;51(5):650-658. https://doi.org/10.1097/SHK.0000000000001197

Werner-Moller P, Sondergaard S, Jakob SM, Takala J, Berger D. Effect of volume status on the estimation of mean systemic filling pressure. J Appl Physiol (1985). 2019;126(6):1503-1513. https://doi.org/10.1152/japplphysiol.00897.2018

2018

Berger D, Takala J. Determinants of systemic venous return and the impact of positive pressure ventilation. Ann Transl Med. 2018;6(18):350. https://doi.org/10.21037/atm.2018.05.27

Cioccari L, Zante B, Bloch A, Berger D, Limacher A, Jakob SM et al. Effects of hemodynamic monitoring using a single-use transesophageal echocardiography probe in critically ill patients - study protocol for a randomized controlled trial. Trials. 2018;19(1):362. https://doi.org/10.1186/s13063-018-2714-4

2017

Bloch A, Kohler A, Posthaus H, Berger D, Santos L, Jakob S et al. Gastrointestinal Impedance Spectroscopy to Detect Hypoperfusion During Hemorrhage. Shock. 2017;48(2):185-195. https://doi.org/10.1097/SHK.0000000000000824

Bloch A, von Arx R, Etter R, Berger D, Kaiser H, Lenz A et al. Impact of Simulator-Based Training in Focused Transesophageal Echocardiography: A Randomized Controlled Trial. Anesth Analg. 2017;125(4):1140-1148. https://doi.org/10.1213/ANE.0000000000002351

Grübler MR, Wigger O, Berger D, Blöchlinger S. Basic concepts of heart-lung interactions during mechanical ventilation. Swiss Med Wkly. 2017;147:w14491. https://doi.org/10.4414/smw.2017.14491

Jakob SM, Bütikofer L, Berger D, Coslovsky M, Takala J. A randomized controlled pilot study to evaluate the effect of an enteral formulation designed to improve gastrointestinal tolerance in the critically ill patient-the SPIRIT trial. Crit Care. 2017;21(1):140. https://doi.org/10.1186/s13054-017-1730-1

Moller PW, Winkler B, Hurni S, Heinisch PP, Bloch A, Sondergaard S et al. Right atrial pressure and venous return during cardiopulmonary bypass. Am J Physiol Heart Circ Physiol. 2017;313(2):H408-H420. https://doi.org/10.1152/ajpheart.00081.2017

Schefold JC, Berger D, Zürcher P, Lensch M, Perren A, Jakob SM et al. Dysphagia in Mechanically Ventilated ICU Patients (DYnAMICS): A Prospective Observational Trial. Crit Care Med. 2017;45(12):2061-2069. https://doi.org/10.1097/CCM.0000000000002765

2016

Berger D, Bloechlinger S, von Haehling S, Doehner W, Takala J, Z'Graggen WJ et al. Dysfunction of respiratory muscles in critically ill patients on the intensive care unit. J Cachexia Sarcopenia Muscle. 2016;7(4):403-12. https://doi.org/10.1002/jcsm.12108

Berger D, Moller PW, Weber A, Bloch A, Bloechlinger S, Haenggi M et al. Effect of PEEP, blood volume, and inspiratory hold maneuvers on venous return. Am J Physiol Heart Circ Physiol. 2016;311(3):H794-806. https://doi.org/10.1152/ajpheart.00931.2015

Berger D, Takala J. Hypotension and hypovolemia during hemodialysis: is the usual suspect innocent?. Crit Care. 2016;20(1):140. https://doi.org/10.1186/s13054-016-1307-4

Wigger O, Bloechlinger S, Berger D, Häner J, Zanchin T, Windecker S et al. Baseline serum bicarbonate levels independently predict short-term mortality in critically ill patients with ischaemic cardiogenic shock. Eur Heart J Acute Cardiovasc Care. 2016;7(1):45-52. https://doi.org/10.1177/2048872616683526

2015

Bloechlinger S, Berger D, Bryner J, Roost E, Jakob S, Dünser MW et al. Changes in Left Ventricular Torsion Early Postoperatively After Aortic Valve Replacement and at Long-Term Follow-up. J Cardiothorac Vasc Anesth. 2015;29(4):860-7. https://doi.org/10.1053/j.jvca.2015.01.010

2014

Berlet T, Etter R, Fehr T, Berger D, Sendi P, Merz TM. Sonographic patterns of lung consolidation in mechanically ventilated patients with and without ventilator-associated pneumonia: a prospective cohort study. J Crit Care. 2014;30(2):327-33. https://doi.org/10.1016/j.jcrc.2014.11.021

Fischer H, Bachmann K, Strunk G, Neuhold S, Zapletal B, Maurer C et al. Translation of ERC resuscitation guidelines into clinical practice by emergency physicians. Scand J Trauma Resusc Emerg Med. 2014;22:9. https://doi.org/10.1186/1757-7241-22-9

2013

Bloechlinger S, Berger D, Bryner J, Wiegand J, Dünser MW, Takala J. Left ventricular torsion abnormalities in septic shock and corrective effect of volume loading: a pilot study. Can J Cardiol. 2013;29(12):1665-71. https://doi.org/10.1016/j.cjca.2013.10.007