Selected Publications

Monti MC, Zeugin J, Koch K, Milenkovic N, Scheurer E, Mercer-Chalmers-Bender K. Adulteration of low-THC products with synthetic cannabinoids: Results from drug checking services. Drug Test Anal. 2022 Jan 7. doi: 10.1002/dta.3220. Online ahead of print

Schneider T, Zurbriggen L, Dieterle M, Mauermann E, Frei P, Mercer-Chalmers-Bender K, Ruppen W. Pain response to cannabidiol in induced acute nociceptive pain, allodynia, and hyperalgesia by using a model mimicking acute pain in healthy adults in a randomized trial (CANAB I). Pain. 2022 Jan 1;163(1):e62-e71. doi: 10.1097/j.pain.0000000000002310.

Köck P, Lang E, Trulley VN, Dechent F, Mercer-Chalmers-Bender K, Frei P, Huber C, Borgwardt S. Cannabidiol Cigarettes as Adjunctive Treatment for Psychotic Disorders - A Randomized, Open-Label Pilot-Study. Front Psychiatry. 2021 Nov 4;12:736822. doi: 10.3389/fpsyt.2021.736822. eCollection 2021.

Senst A, Scheurer E, Gerlach K, Schulz I. Which tissue to take? A retrospective study of the identification success of altered human remains. J Forensic Leg Med. 2021 Nov;84:102271. doi: 10.1016/j.jflm.2021.102271. Epub 2021 Oct 26

Berger C, Bauer M, Wittig H, Scheurer E, Lenz C. Post mortem brain temperature and its influence on quantitative MRI of the brain. Magn Reson Mater Phy. 2021 Oct 29. doi: 10.1007/s10334-021-00971-8.

Monti MC, Scheurer E, Mercer-Chalmers-Bender K. Phase I In Vitro Metabolic Profiling of the Synthetic Cannabinoid Receptor Agonists CUMYL-THPINACA and ADAMANTYL-THPINACA. Metabolites. 2021 Jul 21;11(8):470. doi: 10.3390/metabo11080470.

Lenz C, Berger C, Bauer M, Scheurer E, Birkl C. Sensitivity of fiber orientation dependent R2* to temperature and post mortem interval. Magn Reson Med. 2021 Nov;86(5):2703-2715. doi: 10.1002/mrm.28874. Epup 2021 Jun 4.

Bauer M, Deigendesch N, Wittig H, Scheurer E, Lenz C. Tissue sample analysis for post mortem determination of brain edema. Forensic Sci Int. 2021 Apr 29;323:110808. doi: 10.1016/j.forsciint.2021.110808. Online ahead of print

Wenzel J, Haas SS, Dwyer DB, Ruef A, Oeztuerk OF, Antonucci LA, …, Koutsouleris N, Kambeitz-Ilankovic L, the PRONIA-consortium (…, Egloff L,Lenz C, …). Cognitive subtypes in recent onset psychosis: distinct neurobiological fingerprints? Neuropsychopharmacology 2021 Jul;46(8):1475-1483. doi: 10.1038/s41386-021-00963-1. Epub 2021 Mar 15.

Penzel N, Antonucci LA, Betz LT, Sanfelici R, Weiske J, Pogarell O, ..., Koutsouleris N, Kambeitz J, the PRONIA-consortium (…, Egloff L, Lenz C, …). Association between age of cannabis initiation and gray matter covariance networks in recent onset psychosis. Neuropsychopharmacology 2021 Jul;46(8):1484-1493. doi: 10.1038/s41386-021-00977-9. Epub 2021 Mar 3.

Koutsouleris N, Dwyer DB, Degenhardt F, Maj C, Urquijo-Castro MF, Sanfelici R, …., Theodoridou A, Meisenzahl E; PRONIA Consortium (…., Egloff L, …). Multimodal Machine Learning Workflows for Prediction of Psychosis in Patients With Clinical High-Risk Syndromes and Recent-Onset Depression. JAMA Psychiatry. 2021 Feb 1;78(2):195-209. doi: 10.1001/jamapsychiatry.2020.3604.

Widek T, Genet P, Ehammer T, Schwark T, Urschler M, Scheurer E. Bone age estimation with the Greulich-Pyle atlas using 3T MR images of hand and wrist. Forensic Sci Int. 2021 Feb;319:110654. doi: 10.1016/j.forsciint.2020.110654. Epub 2020 Dec 9.

Egger S, Senst A, Schulz I. Die Rolle des Speichels in der forensischen Genetik. Speichel (Eds. A. Filippi and T. Waltimo) Quintessenz-Verlag, Berlin, Deutschland, 308-318 (2020).

Bauer M, Morales-Orcajo E, Klemm L, Seydewitz R, Fiebach V, Siebert T, Böl M. Biomechanical and microstructural characterisation of the porcine stomach wall: Location- and layer-depent investigations. Acta Biomaterial. 2020 102:83-99. 

Popovic D, Ruef A, Dwyer D, Antonucci L, Eder J, Sanfelici R, … Borgwardt S, Koutsoulris N, the PRONIA-consortium (Sen Dong M, …, Egloff L, Lenz C, … Piccin S). Traces of Trauma:  A Multivariate Pattern Analysis of Childhood Trauma, Brain Structure, and Clinical Phenotypes. Biol Psychiatry. 2020 Dec 1;88(11):829-842. doi: 10.1016/j.biopsych.2020.05.20. Epub 2020 May 26.

Haidl T, Schneider N, Dickmann K, Ruhrmann S, Kaiser N, Rosen M, … Koutsouleris N, Schultze F, PRONIA-consortiums (Betz L, … Egloff L, Lenz C, … Piccin S). Validation of the Bullying Scale for Adults - Results of the PRONIA-study. J Psychiatr Res. 2020 Oct;129:88-97. doi: 10.1016/j.psychires.2020.04.004. Epub 2020 Mai 11.

Koutsouleris N, Dwyer DB, Degenhardt F, Maj C, Urquijo-Castro MF, Sanfelici R, Popovic D, Oeztuerk O, Haas SS, Weiske J, Ruef A, Kambeitz-Ilankovic L, Antonucci LA, Neufang S, Schmidt-Kraepelin C, Ruhrmann S, Penzel N, Kambeitz J, Haidl TK, Rosen M, Chisholm K, Riecher-Rössler A, Egloff L, Schmidt A, Andreou C, Hietala J, Schirmer T, Romer G, Walger P, Franscini M, Traber-Walker N, Schimmelmann BG, Flückiger R, Michel C, Rössler W, Borisov O, Krawitz PM, Heekeren K, Buechler R, Pantelis C, Falkai P, Salokangas RKR, Lencer R, Bertolino A, Borgwardt S, Noethen M, Brambilla P, Wood SJ, Upthegrove R, Schultze-Lutter F, Theodoridou A, Meisenzahl E; Writing Group for the PRONIA Consortium. Multimodal Machine Learning Workflows for Prediction of Psychosis in Patients With Clinical High-Risk Syndromes and Recent-Onset Depression. JAMA Psychiatry. 2020 Dec 2:e203604. doi: 10.1001/jamapsychiatry.2020.3604. Online ahead of print

Stumm CJ, Wittig H, Kalberer NM, Scheurer E. Histomorphological Assessment of isolated Abdominal Organs after targeted Perfusion with the Contrast Agent Angiofil® in Postmortem Computed Tomography Angiography. Forensic Sci Int. 2020 Oct;315:110427. doi: 10.1016/j.forsciint.2020.110427. Epub 2020 Jul 24.

Ralf A, Lubach D, Kousouri N, Winkler C, Schulz I, Roewer L, Purps J, Lessig R, Krajewski P, Ploski R, Dobosz T, Henke L, Henke J, Larmuseau MHD, Kayser M. Identification and characterization of novel rapidly mutating Y-chromosomal short tandem repeat markers. Hum Mutat. 2020 Jun 24. doi: 10.1002/humu.24068

Rosin C, Hennings E, Gerlach K, Wieners K, Winterholler M, Heierle-Duberow A, Tschudin S, Nickel C, Bingisser R. Notfallsituation: häusliche Gewalt. Swiss Medical Forum 2020 April; 20 (15-16):250-255. doi: 10.4414/smf.2020.08495.

Gerlach K, Rossi C. Verkehrsmedizinische Aspekte in der Begutachtung. Medinfo / Infomed Schweizerischer Versicherungsverband SVV. 2020, 3:2-8. www.svv.ch

Alt KW, Tejedor Rodríguez C, Nicklisch N, Roth D, Szécsényi Nagy A, Knipper C, Lindauer S, Held P, de Lagrán ÍGM, Schulz G, Schuerch T, Thieringer F, Brantner P, Brandt G, Israel N, Arcusa Magallón H, Meyer C, Mende BG, Enzmann F, Dresely V, Ramsthaler F, Guillén JIR, Scheurer E, López Montalvo E, Garrido Pena R, Pichler SL, Guerra MAR. A massacre of early Neolithic farmers in the high Pyrenees at Els Trocs, Spain. Sci Rep. 2020 Feb 7;10(1):2131. doi: 10.1038/s41598-020-58483-9

Egger S, Wand D, Scheurer E, Schulz I, Dion D, Balitzki B. Fehlerhafte Geschlechtsbestimmung aufgrund partieller Deletion des Y-Chromosoms. Rechtsmedizin 2020 Feb;30:94-100. doi: 10.1007/s00194-020-00373-5.

Bauer M, Gerlach K, Scheurer E, Lenz C. Analysis of different post mortem assessment methods for cerebral edema. Forensic Sci Int. 2020 Jan 23;308:110164. doi: 10.1016/j.forsciint.2020.110164.

Meier U, Mercer-Chalmers-Bender K, Scheurer E, Dussy F. Development, validation, and application of an LC-MS/MS method for mitragynine and 7-hydroxymitragynine analysis in hair. Drug Test Anal. 2020 Feb;12(2):280-284. doi: 10.1002/dta.2746. Epub 2020 Jan 13.

Lehmann S, Kielba T, Thevis M, Rothschild MA, Mercer-Chalmers-Bender K. Fatalities associated with NPS stimulants in the Greater Cologne area. Int J Legal Med. 2020 Jan; 134(1):229-241. doi: 10.1007/s00414-019-02193-z. Epub 2019 Nov 18.

Beck K, Studerus E, Andreou C, Egloff L, Leanza L, Simon AE, Borgwardt S, Riecher-Rössler A. Clinical and functional ultra-long-term outcome of patients with a clinical high risk (CHR) for psychosis. Eur Psychiatry. 2019 Oct;62:30-37. doi: 10.1016/j.eurpsy.2019.08.005. Epub 2019 Sep 9.

Bornik A, Heinze S, Campana L, Rost Th, Wittig H, Labudde D, Genet P, Grabherr S. Theoretische Grundlagen der forensischen Bildgebung. Rechtsmedizin 2019 Feb;29:1-12. doi: 10.1007/s00194-018-0295-x.

Bykowsky O, Harrisberger F, Schmidt A, Smieskova R, Hauke DJ, Egloff L, Riecher-Rössler A, Fusar-Poli P, Huber CG, Lang UE, Andreou C, Borgwardt S. Association of antidepressants with brain morphology in early stages of psychosis: an imaging genomics approach. Sci Rep. 2019 Jun 11;9(1):8516. doi: 10.1038/s41598-019-44903-y.

Egloff L, Lenz C, Studerus E, Heitz U, Harrisberger F, Smieskova R, Schmidt A, Leanza L, Andreou C, Borgwardt S, Riecher-Rössler A. No associations between medial temporal lobe volumes and verbal learning/memory in emerging psychosis. Eur J Neurosci. 2019 Sep;50(6):3060-3071. doi: 10.1111/ejn.14427. Epub 2019 May 17.

Gaunitz F, Kieliba T, Thevis M, Mercer-Chalmers-Bender K. Solid-phase extraction-liquid chromatography-tandem mass spectrometry method for the qualitative analysis of 61 synthetic cannabinoid metabolites in urine. Drug Test Anal. 2019 Aug 14. doi: 10.1002/dta.2680.

Gaunitz F, Dahm P, Mogler L, Thomas A, Thevis M, Mercer-Chalmers-Bender K. In vitro metabolic profiling of synthetic cannabinoids by pooled human liver microsomes, cytochrome P450 isoenzymes, and Cunninghamella elegans and their detection in urine samples. Anal Bioanal Chem. 2019 Jun;411(16):3561-3579. doi: 10.1007/s00216-019-01837-8. Epub 2019 Jun 10

Gaunitz F, Thomas A, Fietzke M, Franz F, Auwärter V, Thevis M, Mercer-Chalmers-Bender K. Phase I metabolic profiling of the synthetic cannabinoids THJ-018 and THJ-2201 in human urine in comparison to human liver microsome and cytochrome P450 isoenzyme incubation. Int J Legal Med. 2019 Jul;133(4):1049-1064. doi: 10.1007/s00414-018-1964-8. Epub 2018 Dec 18.

Iwersen-Bergmann S, Lehmann S, Heinemann A, Schröder C, Müller A, Jungen H, Andresen-Streichert H, Pueschel K, Vidal C, Mercer-Chalmers-Bender K. Mass poisoning with NPS: 2C-E and Bromo-DrgaonFly. Int J Legal Med. 2019 Jan; 133(1):123-129. doi: 10.1007/s00414-018-1882-9. Epub 2018 Juli 29.

Lehmann S, Sczyslo A, Froch-Cortis J, Rothschild MA, Thevis M, Andresen-Streichert H, Mercer-Chalmers-Bender K. Organ distribution of diclazepam, pyrazolam and 3-fluorophenmetrazine. Forensic Sci Int. 2019 Oct;303:109959. doi: 10.1016/j.forsciint.2019.109959. Epub 2019 Sep 12.

Meier U, Colledge F, Imfeld S, Briellmann T, Mercer-Chalmers-Bender K, Scheurer E, Dussy F. Distribution pattern of common drugs of abuse, ethyl glucuronide, and benzodiazepines in hair across the scalp. Drug Test Anal. 2019 Oct;11(10):1522-1541. doi: 10.1002/dta.2679. Epub 2019 Aug 27.

Menghini-Müller S, Studerus E, Ittig S, Heitz U, Egloff L, Andreou C, Valmaggia LR, Kempton MJ, van der Gaag M, de Haan L, Nelson B, Barrantes-Vidal N, Nordentoft M, Ruhrmann S, Sachs G, Rutten BP, Os JV, Riecher-Rössler A; EU-GEI High Risk Study Group, McGuire P, Valmaggia LR, Kempton MJ, Calem M, Tognin S, Modinos G, de Haan L, van der Gaag M, Velthorst E, Kraan TC, van Dam DS, Burger N, Nelson B, McGorry P, Amminger GP, Pantelis C, Politis A, Goodall J, Borgwardt S, Rapp C, Ittig S, Studerus E, Smieskova R, Bressan R, Gadelha A, Brietzke E, Asevedo G, Asevedo E, Zugman A, Barrantes-Vidal N, Domínguez-Martínez T, Racioppi A, Cristóbal-Narváez P, Kwapil TR, Monsonet M, Kazes M, Daban C, Bourgin J, Gay O, Mam-Lam-Fook C, Krebs MO, Nordholm D, Randers L, Krakauer K, Glenthøj L, Glenthøj B, Nordentoft M, Ruhrmann S, Gebhard D, Arnhold J, Klosterkötter J, Sachs G, Lasser I, Winklbaur B, Delespaul PA, Rutten BP, van Os J. Gender differences of patients at-risk for psychosis regarding symptomatology, drug use, comorbidity and functioning - Results from the EU-GEI study. Eur Psychiatry. 2019 Jun;59:52-59. doi: 10.1016/j.eurpsy.2019.04.007. Epub 2019 May 7.

Mercer-Chalmers-Bender K, Scheurer E, Gerlach K. Neue Psychoaktive Substanzen: einige forensische und rechtliche Aspekte. Suchtmed 21 (6) 1 – 4 (2019)

Ruprecht R, Scheurer E, Lenz C. Systematic review on the characterization of chronic traumatic encephalopathy by MRI and MRS. J Magn Reson Imaging. 2019 Jan;49(1):212-228. doi: 10.1002/jmri.26162. Epub 2018 May 2.

Timm A, Abendschön P, Tölgyesi L, Horn H, Borowska E. Solar-mediated degradation of linezolid and tedizolid under simulated environmental conditions: Kinetics, transformation and toxicity. Chemosphere. 2019 Oct 14;241:125111. doi: 10.1016/j.chemosphere.2019.125111.

Widek T, Genet P, Merkens H, Boldt J, Petrovic A, Vallis J, Scheurer E. Dental age estimation: The chronology of mineralization and eruption of male third molars with 3T MRI. Forensic Sci Int. 2019 Apr;297:228-235. doi: 10.1016/j.forsciint.2019.02.019. Epub 2019 Feb 22

 

Bornik A, Urschler M, Schmalstieg D, Bischof H, Krauskopf A, Schwark T, Scheurer E, Yen K. Integrated computer-aided forensic case analysis, presentation, and documentation based on multimodal 3D data. Forensic Sci Int. 2018 Jun;287:12-24. doi: 10.1016/j.forsciint.2018.03.031. Epub 2018 Mar 23.

Gaunitz F, Lehmann S, Thomas A, Thevis M, Rothschild MA, Mercer-Chalmers-Bender K. Post-mortem distribution of the synthetic cannabinoid MDMB-CHMICA and its metabolites in a case of combined drug intoxication. Int J Legal Med. 2018 Sep 15. doi: 10.1007/s00414-018-1911-8.

Grabherr S, Heinemann A, Vogel H, Rutty G, Morgan B, Wozniak K, Dedouit F, Fischer F, Lochner S, Wittig H, Guglielmi G, Eplinius F, Michaud K, Palmiere C, Chevallier C, Mangin P, Grimm JM. Postmortem CT Angiography Compared with Autopsy: A Forensic Multicenter Study. Radiology. 2018 Juli;288(1):270-276. doi: 10.1148/radiol.2018170559. Epub 2018 May 1.

Meier U, Dussy F, Scheurer E, Mercer-Chalmers-Bender K, Hangartner S. Cannabinoid concentrations in blood and urine after smoking cannabidiol joints. Forensic Sci Int. 2018 Oct;291:62-67. doi: 10.1016/j.forsciint.2018.08.009. Epub 2018 Aug 11

Meier U, Briellmann T, Scheurer E, Dussy F. Sample preparation method for the combined extraction of ethyl glucuronide and drugs of abuse in hair. Drug Test Anal. 2018 Apr;10(4):701-710. doi: 10.1002/dta.2314. Epub 2017 Nov 27.

Neumayer B, Widek T, Stollberger R, Scheurer E. Reproducibility of relaxometry of human lumbar vertebrae at 3 Tesla using 1 H MR spectroscopy. J Magn Reson Imaging. 2018 Jul;48(1):153-159. doi: 10.1002/jmri.25912. Epub 2017 Dec 12.

Lehmann S, Schulze B, Thomas A, Kamphausen T, Thevis M, Rothschild MA, Mercer-Chalmers-Bender K. Organ distribution of 4-MEC, MDPV, methoxetamine and α-PVP: comparison of QuEChERS and SPE. Forensic Toxicol. (2018) doi:10.1007/s11419-018-0408-y.

Weiss G, Wittig H, Scheurer E, Ruprecht R, Lenz C. Identification of deceased based on sternal bone computed tomography features. Forensic Sci Int 2018 May;286:233-238. doi: 10.1016/j.forsciint.2018.03.018. Epub 2018 Mar 17.

Wiesenmueller S, Cierniak P, Juebner M, Koerner E, Hegemann D, Mercer-Chalmers Bender K. Tailored antimicrobial activity and long-term cytocompatibility of plasma polymer silver nanocomposites. J Biomater Appl. 2018 Sep;33(3):327-339. doi: 10.1177/0885328218793488.

Heinemann A, Grabherr S, Dedouit F, Wozniak K, Fischer F, Wittig H, Grimm J, Vogel H and Tech Working Grp P-M. The impact of multiphase post-mortem CT-angiography (MPMCTA) for investigating fatal outcomes of medical interventions. J Forensic Radiology and Imaging 8: 38-44. (2017) doi:10.1016/j.jofri.2017.03.008.

Lehmann S, Kieliba T, Beike J, Thevis M and Mercer-Chalmers-Bender K. Determination of 74 new psychoactive substances in serum using automated in-line solid-phase extraction-liquid chromatography-tandem mass spectrometry. J Chromatography B 1064: 124-138. (2017) doi:10.1016/j.jchromb.2017.09.003.

Meier U, Briellmann T, Scheurer E and Dussy F. Distribution pattern of ethyl glucuronide and caffeine concentrations over the scalp of a single person in a forensic context. Drug Test Anal 9: 1594-1603.(2017) doi:10.1002/dta.2186.

Neumayer B, Amerstorfer E, Diwoky C, Lindtner R A, Wadl E, Scheurer E, Weinberg A M and Stollberger R. Assessment of pharmacokinetics for microvessel proliferation by DCE-MRI for early detection of physeal bone bridge formation in an animal model. MAGMA 30: 417-427. (2017) doi:10.1007/s10334-017-0615-2.

Offenmüller G, Grossenbacher R, Dion D and Balitzki B. Automatisierung im forensischen DNA-Labor. Rechtsmed 27:266-272. (2017) doi:10.1007/s00194-017-0165-y.

Ogris K, Petrovic A, Scheicher S, Sprenger H, Urschler M, Hassler E M, Yen K and Scheurer E. Detection and volume estimation of artificial hematomas in the subcutaneous fatty tissue: comparison of different MR sequences at 3.0 T. Forensic Sci Med Pathol 13: 135-144. (2017) doi:10.1007/s12024-017-9847-8.

Panzer S, Wittig H, Zesch S, Rosendahl W, Blache S, Muller-Gerbl M and Hotz G. Evidence of neurofibromatosis type 1 in a multi-morbid Inca child mummy: A paleoradiological investigation using computed tomography. Plos One 12: e0175000. (2017) doi:10.1371/journal.pone.0175000.

Rost T, Kalberer N and Scheurer E. A user-friendly technical set-up for infrared photography of forensic findings. Forensic Sci Int 278: 148-155. (2017) doi:10.1016/j.forsciint.2017.07.001.

Wittig H, Grünewald S, Gerlach K, Dussy F and Scheurer E. Suizidale Drosselung mittels Kabelbinder. Rechtsmed 27: 433-437. (2017) doi:10.1007/s00194-017-0196-4.

Buchkapitel

Panzer S, Wittig H, Zesch S, Rosendahl W, Blache S, Müller-Gerbl M, Brust A and Hotz G. Krankheiten und Gewalt – zur Computertomographie eines Inka-Mumienbündels aus Basel. Tatorte der Vergangenheit Archäologie und Forensik (Eds. W. Rosendahl and B. Madea) Konrad Theiss Verlag, Darmstadt, Deutschland

 

Baron K, Neumayer B, Amerstorfer E, Scheurer E, Diwoky C, Stollberger R, Sprenger H and Weinberg A M. Time-Dependent Changes in T1 during Fracture Healing in Juvenile Rats: A Quantitative MR Approach. Plos One 11. (2016) doi:10.1371/journal.pone.0164284.

Baron K, Neumayer B, Widek T, Schick F, Scheicher S, Hassler E and Scheurer E. Quantitative MR imaging in fracture dating-Initial results. Forensic Science International 261: 61-69. (2016) doi:10.1016/j.forsciint.2016.01.020.

Dussy F E, Hangartner S, Hamberg C, Berchtold C, Scherer U, Schlotterbeck G, Wyler D and Briellmann T A. An Acute Ocfentanil Fatality: A Case Report with Postmortem Concentrations. Journal of analytical toxicology 40: 761-766. (2016).

Hangartner S, Steiner J, Dussy F, Moeckli R, Gerlach K and Briellmann T. A suicide involving intraperitoneal injection of pentobarbital. International Journal of Legal Medicine 130: 1217-1222. (2016) doi:10.1007/s00414-015-1231-1.

Lötscher M, Voser B, Dittmann V and Gerlach K. Sterbehilfe: Der assistierte Suizid. Kriminalistik Heft 3186-196. (2016).

Petrovic A, Krauskopf A, Hassler E, Stollberger R and Scheurer E. Time related changes of T-1, T-2, and T-2* of human blood in vitro. Forensic Science International 262: 11-17. (2016) doi:10.1016/j.forsciint.2016.02.032.

Urschler M, Krauskopf A, Widek T, Sorantin E, Ehammer T, Borkenstein M, Yen K and Scheurer E. Applicability of Greulich-Pyle and Tanner-Whitehouse grading methods to MRI when assessing hand bone age in forensic age estimation: A pilot study. Forensic Science International 266: 281-288. (2016) doi:10.1016/j.forsciint.2016.06.016.

Buchkapitel

Wittig H, C. S, F. E and L. H. Histology after postmortem Angiography. Atlas of Postmortem Angiography (ed. by S. Grabherr, J. Grimm and A. Heinemann) Springer, Cham.(2016).