Digital Analysis of Biomarkers

Dr. Marta Nowak engages in translational research projects focused on the digital assessment of both established and novel biomarkers to enhance the understanding of tumor biology and improve patient stratification. The goal is to use digital image analysis applications to develop algorithmic prototypes that could standardize and streamline pathology workflows. Her primary research areas include the evaluation of tumor-infiltrating lymphocytes (TILs) and the expression analysis of mismatch repair proteins.

Marta Nowak

Dr. Marta Nowak

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Key Papers

Single-cell AI-based detection and prognostic and predictive value of DNA mismatch repair deficiency in colorectal cancer.
Nowak M, Jabbar F, Rodewald AK, Gneo L, Tomasevic T, Harkin A, Iveson T, Saunders M, Kerr R, Oein K, Maka N, Hay J, Edwards J, Tomlinson I, Sansom O, Kelly C, Pezzella F, Kerr D, Easton A, Domingo E; TransSCOT group; Koelzer VH, Church DN.
Cell Rep Med. 2024 Sep 17;5(9):101727. doi: 10.1016/j.xcrm.2024.101727.

Establishing standardized immune phenotyping of metastatic melanoma by digital pathology.
Sobottka B, Nowak M, Frei AL, Haberecker M, Merki S; Tumor Profiler consortium; Levesque MP, Dummer R, Moch H, Koelzer VH.
Lab Invest. 2021 Dec;101(12):1561-1570. doi: 10.1038/s41374-021-00653-y. Epub 2021 Aug 26