The Department of Biomedical Engineering fosters a culture where scientific developments in medical technology are translated into actual application. These activities are currently exemplified by a steadily growing number of Spin-Off companies:



ACTHERA is a Swiss biotech company which provides a therapeutic platform based on Hard-Shelled Liposomes (HSLs) that can contain a broad variety of therapeutically active ingredients. ACTHERA’s unique and highly innovative release mechanism will allow the release of active ingredients at therapeutic sites, thus revealing an extraordinarily wide field of applications to transform numerous therapeutic areas.



AD MIRABILES AG develops and sells patient specific implants for all kinds of indications, in particular we focus on CMF applications. Besides our current product offering, namely customized PEEK implants, we are committed to continuously develop our product and service portfolio further, in order to improve the quality of life of the patients.



For thousands of years, man has cut bone with saws of all kinds. But today we have the technology to finally reinvent bone surgery. That's why we founded AOT, the first company to cut bone and hard tissue with laser, more specifically with robot-assisted cold photoablation.



The Bottmedical AG develops two systems: NaturAligner®, a bio-based plastic splint for the correction of malpositioned teeth, and TOFI, a unique ultra-thin nano-sensor that works as a tactile interface between the tongue and a smartphone app. This system will enable interactive and fun training of myofunctional tongue motor skills to improve tongue tension and subconscious control during the night, thus preventing chronic snoring and mild sleep apnea.

Bottneuro AG


Bottneuro AG develops plant-based, ultra-thin neural implants for the spine and brain. Patients suffering from chronic neuropathic pain, Alzheimer’s and other neurodegenerative diseases will benefit from our NENI® neuromodulation technology. Bottneuro AG is a deep-tech spin-off with an IP portfolio related to the core polymer thin-film technology. The team can fall back on several years of experience in management, product design, marketing, business development, polymer nanotechnology and neurosurgery.



BioInitials, founded in April 2019, develops non-invasive medical devices to monitor the health-state of the oral cavity. Based on biochemical sensors we will evaluate saliva biomarkers to identify risk factors related to periodontitis.



DBI aims to uncover the full potential of Molecular Breath Analysis to advance precision medicine and make it available for general health care. We implement Molecular Breath Analysis by combining mass-spectrometry with advanced Artificial Intelligence to turn it into a powerful tool for medical research and daily clinical practice.



Di Meliora AG is a spin-off of the University of Basel. Its BOTTICELLI implant system helps young dentists, who want to start placing dental implants by reducing complexity and increasing treatability. The company successfully rose funds early 2018 and is prototyping its first products. Through its patents it has also received a grant from the Swiss Federal Government for a CTI project to develop a ceramic implant.



Diffuse with its software tool _Specto_ is dedicated on advanced visualisation of three-dimensional medical data. The proprietary Specto visualisation software implement state of the art photorealistic raytracing but still scalable enough to drive Virtual Reality goggles in real-time i.e. 180 frames per second. Specto has already been successfully applied in dozens of surgical interventions.


MIMEDIS (now part of Medartis AG)

We provide patient-specific implant designs that consider given anatomical guidelines. Having this design, we produce and deliver personalized implants within few working days using highly flexible production processes such as “3D Printing”.



GPS for dentists.
Mininavident has developed a mobile 3-D navigation system that allows dentists to see exactly and in real time where and how they drill into the jaw during implantation. This makes the treatments shorter, easier and cheaper. The company, a spin-off of the University Hospital Basel and the University of Applied Sciences Northwestern Switzerland, has moved from the Innovation Center in Allschwil to Liestal for the launch of the product.



In cooperation with the Hightech-Research-Center (HFZ) at the Department of Biomedical Engineering (DBE) of University of Basel, University Hospital Basel and other clinics in Switzerland and abroad we develop innovative solutions in the area of Computer Assisted Surgery and Medical Additive Manufacturing and thus take the future to the clinic.