Kesenheimer EM, Wendebourg MJ, Weidensteiner C, Sander L, Weigel M, Haas T, Fischer D, Neuwirth C, Braun N, Weber M, Granziera C, Sinnreich M, Bieri O, Schlaeger R.
Spinal Cord Gray matter atrophy is associated with disability in Spinal muscular atrophy.
Journal of Neurology. 2024. acc for publication. DOI: 10.1007/s00415-024-12740-3 read
 
Wendebourg MJ, Kesenheimer E, Sander L, Weigel M, Weidensteiner C, Haas T, Madoerin P, Diebold M, Deigendesch N, Neuhaus D, Naumann N, Neuwirth C, Braun N, Weber M, Granziera C, Scheurer E, Lenz C, Schweikert K, Sinnreich M, Lieb J, Bieri O, Schlaeger R.
The Lateral Corticospinal Tract Sign: An MRI Marker for Amyotrophic Lateral Sclerosis.
Radiology. 2024 Sep;312(3):e231630. doi: 10.1148/radiol.231630. PMID: 39287519. read
 
Neuhaus D, Rost T, Haas T, Wendebourg MJ, Schulze K, Schlaeger R, Scheurer E, Lenz C.
Comparative analysis of in situ and ex situ postmortem brain MRI: Evaluating volumetry, DTI, and relaxometry.
Magn Reson Med. 2025 Jan;93(1):213-227. doi: 10.1002/mrm.30264. Epub 2024 Sep 9. PMID: 39250425. read
 
Steiner L, Tscherter A, Henzi B, Branca M, Carda S, Enzmann C, Fluss J, Jacquier D, Neuwirth C, Ripellino P, Scheidegger O, Schlaeger R, Schreiner B, Stettner GM, Klein A; Swiss-Reg-NMD Group. Chronic Pain in Patients with Spinal Muscular Atrophy in Switzerland: A Query to the Spinal Muscular Atrophy Registry. J Clin Med. 2024 May 9;13(10):2798. doi: 10.3390/jcm13102798. PMID: 38792340; PMCID: PMC11122245. read
 
Wendebourg MJ, Weigel M, Weidensteiner C, Sander L, Kesenheimer E, Naumann N, Haas T, Madoerin P, Braun N, Neuwirth C, Weber M, Jahn K, Kappos L, Granziera C, Schweikert K, Sinnreich M, Bieri O, Schlaeger R.
Cervical and thoracic spinal cord gray matter atrophy is associated with disability in patients with amyotrophic lateral sclerosis.
Eur J Neurol. 2024 Jun;31(6):e16268. doi:10.1111/ene.16268. Epub 2024 Mar 11. PMID: 38465478; PMCID: PMC11235652. read
 
Tsagkas C, Huck-Horvath A, Cagol A, Haas T, Amann M, Barakovic M, Ruberte E, Melie-Garcia L, Weigel M, Pezold S, Schlaeger R, Kuhle J, Sprenger T, Kappos L, Bieri O, Cattin P, Granziera C, Parmar K.
Longitudinal assessment of cervical spinal cord compartments in multiple sclerosis.
Mult Scler Relat Disord. 2023 Mar;71:104545. doi: 10.1016/j.msard.2023.104545. Epub 2023 Feb 3. PMID:36758461. read
 
Tsagkas C, Huck-Horvath A, Cagol A, Haas T, Barakovic M, Amann M, Ruberte E, Melie-Garcia L, Weigel M, Pezold S, Schlaeger R, Kuhle J, Sprenger T, Kappos L, Bieri O, Cattin P, Granziera C, Parmar K.
Anterior horn atrophy in the cervical spinal cord: A new biomarker in progressive multiple sclerosis.
Mult Scler. 2023 May;29(6):702-718. doi: 10.1177/13524585221139152. Epub 2022 Dec 22. PMID:36550626. read
 
Schlaeger R*, Hardmeier M*, Lascano AM, Toffolet L, Schindler C, Gobbi C, Lalive P, Kuhle J, Kappos L, Fuhr P.
Prognostic biomarkers in primary progressive multiple sclerosis: Validating and scrutinizing multimodal evoked potentials.
Clin Neurophysiol. 2022 May;137:152-158. doi: 10.1016/j.clinph.2022.02.019. Epub 2022 Mar 7. PMID: 35316624.(*equal contribution) read
 
Oechtering J, Lincke T, Schaedelin S, Décard BF, Maceski A, Orleth A, Meier S, Willemse E, Buchmann A, Khalil M, Derfuss T, Benkert P, Heijnen I, Regeniter A, Müller S, Achtnichts L, Lalive P, Salmen A, Pot C, Gobbi C, Kappos L, Granziera C, Leppert D, Schlaeger R, Lieb JM, Kuhle J; Swiss MS Cohort Study.
Intrathecal IgM Synthesis Is Associated with Spinal Cord Manifestation and Neuronal Injury in Early MS.
Ann Neurol. 2022 Jun;91(6):814-820. doi: 10.1002/ana.26348. Epub 2022 Apr 9. PMID: 35293622; PMCID: PMC9320956. read
 
Müller J, Sinnecker T, Wendebourg MJ, Schläger R, Kuhle J, Schädelin S, Benkert P, Derfuss T, Cattin P, Jud C, Spiess F, Amann M, Lincke T, Barakovic M, Cagol A, Tsagkas C, Parmar K, Pröbstel AK, Reimann S, Asseyer S, Duchow A, Brandt A, Ruprecht K, Hadjikhani N, Fukumoto S, Watanabe M, Masaki K, Matsushita T, Isobe N, Kira JI, Kappos L, Würfel J, Granziera C, Paul F, Yaldizli Ö.
Choroid Plexus Volume in Multiple Sclerosis vs Neuromyelitis Optica Spectrum Disorder: A Retrospective, Cross-sectional Analysis.
Neurol Neuroimmunol Neuroinflamm. 2022 Feb 25;9(3):e1147. doi: 10.1212/NXI.0000000000001147. PMID:35217580; PMCID: PMC8883575. read
 
Wendebourg MJ, Weigel M, Richter L, Gocheva V, Hafner P, Orsini AL, Crepulja V, Schmidt S, Huck A, Oechtering J, Blatow M, Haas T, Granziera C, Kappos L, Cattin P, Bieri O, Fischer D, Schlaeger R.
Spinal cord gray matter atrophy is associated with functional decline in post-polio syndrome.
Eur J Neurol. 2022 May;29(5):1435-1445. doi: 10.1111/ene.15261. Epub 2022 Mar 3. PMID: 35102676; PMCID: PMC9310958. read
 
Kesenheimer EM, Wendebourg MJ, Weigel M, Weidensteiner C, Haas T, Richter L, Sander L, Horvath A, Barakovic M, Cattin P, Granziera C, Bieri O, Schlaeger R.
Normalization of Spinal Cord Total Cross-Sectional and Gray Matter Areas as Quantified With Radially Sampled Averaged Magnetization Inversion Recovery Acquisitions.
Front Neurol. 2021 Mar 25;12:637198. doi: 10.3389/fneur.2021.637198. PMID: 33841307; PMCID: PMC8027254. read
 
Sander L, Horvath A, Pezold S, Andermatt S, Amann M, Sinnecker T, Wendebourg MJ, Kesenheimer E, Yaldizli Ö, Kappos L, Granziera C, Wuerfel J, Cattin P, Schlaeger R.
Improving Accuracy of Brainstem MRI Volumetry: Effects of Age and Sex, and Normalization Strategies.
Front Neurosci. 2020 Dec 23;14:609422. doi: 10.3389/fnins.2020.609422. PMID: 33424541; PMCID: PMC7785816. read
 
Weigel M, Haas T, Wendebourg MJ, Schlaeger R, Bieri O.
Imaging of the thoracic spinal cord using radially sampled averaged magnetization inversion recovery acquisitions.
J Neurosci Methods. 2020 Sep 1;343:108825. doi: 10.1016/j.jneumeth.2020.108825. Epub 2020 Jun 21. PMID: 32580062. read
 
Wendebourg MJ, Nagy S, Derfuss T, Parmar K, Schlaeger R.
Magnetic resonance imaging in immune-mediated myelopathies.
J Neurol. 2020 May;267(5):1233-1244. doi: 10.1007/s00415-019-09206-2. PMID: 30694379. read

Weigel M, Haas T, Wendebourg MJ, Schlaeger R, Bieri O.
Imaging of the thoracic spinal cord using radially sampled averaged magnetization inversion recovery acquisitions
J Neurosci Methods. 2020 Sep 1;343:108825. doi: 10.1016/j.jneumeth.2020.108825. Epub 2020 Jun 21. read

Sander L, Horvath A, Pezold S, Andermatt S, Amann M, Sinnecker T, Wendebourg MJ, Kesenheimer E, Yaldizli Ö, Kappos L, Granziera C, Wuerfel J, Cattin P, Schlaeger R.
Improving Accuracy of Brainstem MRI Volumetry: Effects of Age and Sex, and Normalization Strategies
Front Neurosci. 2020 Dec 23;14:609422. doi: 10.3389/fnins.2020.609422. eCollection 2020. read

Wendebourg MJ, Nagy S, Derfuss T, Parmar K, Schlaeger R.
Magnetic resonance imaging in immune-mediated myelopathies
J Neurol. 2020 May;267(5):1233-1244. doi: 10.1007/s00415-019-09206-2. Epub 2019 Jan 29. read

Sander L, Horvath L, Pezold S, Amann M, Andermatt S, Yaldizli O, Wuerfel J, Kappos L, Granziera C, Gobbi C, Kuhle J, Cattin P, Schlaeger R
Medulla oblongata atrophy in Early Stage Multiple Sclerosis.
Neurology. 2020;94(15_supplement):4278. DOI: 10.1212/WNL.94.15_supplement.4278 read

Sander L, Pezold S, Andermatt S, Amann M, Meier D, Wendebourg MJ, Sinnecker T, Radue EW, Naegelin Y, Granziera C, Kappos L, Wuerfel J, Cattin P, Schlaeger R; Alzheimer's Disease Neuroimaging Initiative.
Accurate, rapid and reliable, fully automated MRI brainstem segmentation for application in multiple sclerosis and neurodegenerative diseases
Hum Brain Mapp. 2019 Oct 1;40(14):4091-4104. doi: 10.1002/hbm.24687. Epub 2019 Jun 17. read

Schlaeger R, Papinutto N, Zhu A, Datta E, Bevan CJ, Caverzasi E, Jordan KM, Lobach I, Keshavan A, Bischof A, Kirkish G, Stern W, Devereux M, Baker N, Bove R, Gelfand JM, Graves JS, Green AJ, Waubant E, et al.
Spinal cord gray matter atrophy is detectable at an early stage of Multiple Sclerosis.
Cutting edge developments in MS Research. Actrims. 2017

Ciccarelli, Olga, Cohen JA, Reingold, Stephen C., Weinshenker BG, & International Conference on Spinal Cord Involvement and Imaging in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders
Spinal cord involvement in multiple sclerosis and neuromyelitis optica spectrum disorders
The Lancet Neurology, 2019 18(2), 185–197. https://doi.org/10.1016/s1474-4422(18)30460-5 read

Sinnecker T, Granziera C, Wuerfel J, Schlaeger R.
Future Brain and Spinal Cord Volumetric Imaging in the Clinic for Monitoring Treatment Response in MS
Curr Treat Options Neurol. 2018 Apr 20;20(6):17. doi: 10.1007/s11940-018-0504-7. read

Datta E, Papinutto N, Schlaeger R, Zhu A, Carballido-Gamio J, Henry RG.
Gray matter segmentation of the spinal cord with active contours in MR images
Neuroimage. 2017 Feb 15;147:788-799. doi: 10.1016/j.neuroimage.2016.07.062. Epub 2016 Aug 2. read

Prados F, Ashburner J, Blaiotta C, Brosch T, Carballido-Gamio J, Cardoso MJ, Conrad BN, Datta E, Dávid G, Leener B, Dupont SM, Freund P, Wheeler-Kingshott CAMG, Grussu F, Henry R, Landman BA, Ljungberg E, Lyttle B, Ourselin S, Papinutto N, Saporito S, Schlaeger R, Smith SA, Summers P, Tam R, Yiannakas MC, Zhu A, Cohen-Adad J.
Spinal cord grey matter segmentation challenge
Neuroimage. 2017 May 15;152:312-329. doi: 10.1016/j.neuroimage.2017.03.010. Epub 2017 Mar 7. read

Isobe N, Keshavan A, Gourraud PA, Zhu AH, Datta E, Schlaeger R, Caillier SJ, Santaniello A, Lizée A, Himmelstein DS, Baranzini SE, Hollenbach J, Cree BA, Hauser SL, Oksenberg JR, Henry RG.
Association of HLA Genetic Risk Burden With Disease Phenotypes in Multiple Sclerosis
JAMA Neurol. 2016 Jul 1;73(7):795-802. doi: 10.1001/jamaneurol.2016.0980.

Schlaeger R, Hardmeier M, D'Souza M, Grize L, Schindler C, Kappos L, Fuhr P.
Monitoring multiple sclerosis by multimodal evoked potentials: Numerically versus ordinally scaled scoring systems
Clin Neurophysiol. 2016 Mar;127(3):1864-71. doi: 10.1016/j.clinph.2015.11.041. Epub 2015 Dec 10. read

Keshavan A, Paul F, Beyer MK, Zhu AH, Papinutto N, Shinohara RT, Stern W, Amann M, Bakshi R, Bischof A, Carriero A, Comabella M, Crane JC, D'Alfonso S, Demaerel P, Dubois B, Filippi M, Fleischer V, Fontaine B, Gaetano L, Goris A, Graetz C, Gröger A, Groppa S, Hafler DA, Harbo HF, Hemmer B, Jordan K, Kappos L, Kirkish G, Llufriu S, Magon S, Martinelli-Boneschi F, McCauley JL, Montalban X, Mühlau M, Pelletier D, Pattany PM, Pericak-Vance M, Cournu-Rebeix I, Rocca MA, Rovira A, Schlaeger R, Saiz A, Sprenger T, Stecco A, Uitdehaag BMJ, Villoslada P, Wattjes MP, Weiner H, Wuerfel J, Zimmer C, Zipp F; International Multiple Sclerosis Genetics Consortium. Electronic address: AIVINSON@PARTNERS.ORG; Hauser SL, Oksenberg JR, Henry RG.
Power estimation for non-standardized multisite studies
Neuroimage. 2016 Jul 1;134:281-294. doi: 10.1016/j.neuroimage.2016.03.051. Epub 2016 Apr 1. read

Papinutto N, Schlaeger R, Panara V, Caverzasi E, Ahn S, Johnson KJ, Zhu AH, Stern WA, Laub G, Hauser SL, Henry RG.
2D phase-sensitive inversion recovery imaging to measure in vivo spinal cord gray and white matter areas in clinically feasible acquisition times
J Magn Reson Imaging. 2015 Sep;42(3):698-708. doi: 10.1002/jmri.24819. Epub 2014 Dec 8. read

Papinutto N, Schlaeger R, Panara V, Zhu AH, Caverzasi E, Stern WA, Hauser SL, Henry RG.
Age, gender and normalization covariates for spinal cord gray matter and total cross-sectional areas at cervical and thoracic levels: A 2D phase sensitive inversion recovery imaging study
PLoS One. 2015 Mar 17;10(3):e0118576. doi: 10.1371/journal.pone.0118576. eCollection 2015. read

Schlaeger R, Papinutto N, Zhu AH, Lobach IV, Bevan CJ, Bucci M, Castellano A, Gelfand JM, Graves JS, Green AJ, Jordan KM, Keshavan A, Panara V, Stern WA, von Büdingen HC, Waubant E, Goodin DS, Cree BA, Hauser SL, Henry RG.
Association Between Thoracic Spinal Cord Gray Matter Atrophy and Disability in Multiple Sclerosis
JAMA Neurol. 2015 Aug;72(8):897-904. doi: 10.1001/jamaneurol.2015.0993. read

Müller U, Ulmer S, Schlaeger R, Ahlhelm F.
[Pediatric intraspinal neoplasms]
Radiologe. 2014 Aug;54(8):792-9. doi: 10.1007/s00117-014-2669-8. read

Schlaeger R, Lieb JM, Shariat K, Ahlhelm FJ.
[Postoperative spine]
Radiologe. 2014 Nov;54(11):1093-102. doi: 10.1007/s00117-014-2727-2. read

Schlaeger R, Papinutto N, Panara V, Bevan C, Lobach IV, Bucci M, Caverzasi E, Gelfand JM, Green AJ, Jordan KM, Stern WA, von Büdingen HC, Waubant E, Zhu AH, Goodin DS, Cree BA, Hauser SL, Henry RG.
Spinal cord gray matter atrophy correlates with multiple sclerosis disability.
Ann Neurol. 2014 Oct;76(4):568-80. doi: 10.1002/ana.24241. Epub 2014 Aug 21. PMID: 25087920; PMCID: PMC5316412. read

Schlaeger R, Schindler C, Grize L, Dellas S, Radue EW, Kappos L, Fuhr P.
Combined visual and motor evoked potentials predict multiple sclerosis disability after 20 years
Mult Scler. 2014 Sep;20(10):1348-54. doi: 10.1177/1352458514525867. Epub 2014 Feb 26. read

Schlaeger R, D'Souza M, Schindler C, Grize L, Kappos L, Fuhr P.
Electrophysiological markers and predictors of the disease course in primary progressive multiple sclerosis
Mult Scler. 2014 Jan;20(1):51-6. doi: 10.1177/1352458513490543. Epub 2013 Jun 11. read

Schlaeger R, D'Souza M, Schindler C, Grize L, Kappos L, Fuhr P.
Prediction of MS disability by multimodal evoked potentials: investigation during relapse or in the relapse-free interval?
Clin Neurophysiol. 2014 Sep;125(9):1889-92. doi: 10.1016/j.clinph.2013.12.117. Epub 2014 Jan 31. read

Ban,W, Cree,BAC, Li,Y, Schlaeger,R, Zhu,A, Jakary,A, Leppert,D, Seneca,N, Nelson,SJ, Henry,RG
Exploring Phase Contrast Mechanisms of Multiple Sclerosis Lesions: Initial Evidence from MR Spectroscopic Image at 7T.
ECTRIMS/ACTRIMS Multiple Sclerosis Journal, 2014, 45–46.

Schlaeger R, Hardmeier M, Fuhr P.
Superficial brain stimulation in multiple sclerosis
Handb Clin Neurol. 2013;116:577-84. doi: 10.1016/B978-0-444-53497-2.00046-2. read

Schlaeger R, D'Souza M, Schindler C, Grize L, Kappos L, Fuhr P.
Combined evoked potentials as markers and predictors of disability in early multiple sclerosis
Clin Neurophysiol. 2012 Feb;123(2):406-10. doi: 10.1016/j.clinph.2011.06.021. Epub 2011 Jul 22. read

Schlaeger R, D'Souza M, Schindler C, Grize L, Dellas S, Radue EW, Kappos L, Fuhr P.
Prediction of long-term disability in multiple sclerosis
Mult Scler. 2012 Jan;18(1):31-8. doi: 10.1177/1352458511416836. Epub 2011 Aug 25. read

Schlaeger R, Naegelin Y, Welge-Lüssen A, Straumann D, Gass A, Fluri F, Baumann T.
Acute vertigo with double vision - brainstem stroke or stroke mimic?
Cerebrovasc Dis. 2010;30(6):626-7. doi: 10.1159/000320256. Epub 2010 Oct 15. read

Schlaeger R, Sollberger M.
An unusual cause of isolated vomiting
Neurology. 2010 Oct 5;75(14):1303. doi: 10.1212/WNL.0b013e3181f61354. read

Schläger R, Mehling M, Gass A, Kuhle J
Liquordiagnostik der Multiplen Sklerose - Diagnose und Differentialdiagnose.
psychoneuro 2008; 34(6/07): 293-305 DOI: 10.1055/s-0028-1083831 read