The group develops computational tools to analyze imaging data of tissues to quantify the effect of diseases. Challenges are typically the handling of large data sets and complex morphological microstructures, such as the cancerous vessel tree. Current research activities include:

• the combination of µCT and histology data from human bone specimens to evaluate the effectiveness of grafting materials
• the characterization of tumor tissue and its vascularization using multimodal imaging
• the morphological investigation of kidney vascularization and human brain tissue, particularly hippocampus and cerebellum
• The projects are focused on the interpretation and the quantification of tomography data sets for medical purposes.

Keywords: Regenerative medicine, cancer research, neuropathology, synchrotron radiation, tissue characterization, vessel tree vectorization, feature-based segmentation, 2D-3D registration, level set methods, modelling and simulation