Exhaled Breath Analysis in Pediatric Patients exposed to Environmental Tobacco Smoke (EBATS): a Pilot Study

Exposure of children to environmental tobacco smoke (ETS) can lead to serious health consequences, impacting upon the lung development and the risk of later respiratory diseases. While there is strong evidence confirming detrimental effects of ETS from clinical observational studies, much remains to be known at the molecular level. This can help to improve our understanding of mechanisms by which ETS affects the children’s health.

The aim of this single-center study is to compare the metabolic profile of children exposed to ETS with the profile of non-exposed children by breath analysis with secondary electrospray ionization high-resolution mass spectrometry (SESI-HRMS).