Scientific Publications
Peer-reviewed articles
La Rosa F, Beck ES, Maranzano J, Todea RA, van Gelderen P, de Zwart JA, Luciano NJ, Duyn JH, Thiran JP, Granziera C, Reich DS, Sati P, Cuadra MB.
Multiple sclerosis cortical lesion detection with deep learning at ultra-high-field MRI
NMR Biomed. 2022 Mar 16:e4730. doi: 10.1002/nbm.4730. PMID: 35297114
Oechtering J, Lincke T, Schaedelin S, Décard BF, Maceski A, Orleth A, Meier S, Willemse E, Buchmann A, Khalil M, Derfuss T, Benkert P, Heijnen I, Regeniter A, Müller S, Achtnichts L, Lalive P, Salmen A, Pot C, Gobbi C, Kappos L, Granziera C, Leppert D, Schlaeger R, Lieb JM, Kuhle J; Swiss MS Cohort Study.
Intracthecal IgM synthesis is associated with spinal cord manifestation and neuronal injury in early MS
Ann Neurol. 2022 Mar 16. doi: 10.1002/ana.26348. PMID: 35293622
Müller J, Sinnecker T, Wendebourg MJ, Schläger R, Kuhle J, Schädelin S, Benkert P, Derfuss T, Cattin P, Jud C, Spiess F, Amann M, Lincke T, Barakovic M, Cagol A, Tsagkas C, Parmar K, Pröbstel AK, Reimann S, Asseyer S, Duchow A, Brandt A, Ruprecht K, Hadjikhani N, Fukumoto S, Watanabe M, Masaki K, Matsushita T, Isobe N, Kira JI, Kappos L, Würfel J, Granziera C, Paul F, Yaldizli Ö.
Choroid Plexus Volume in Multiple Sclerosis vs Neuromyelitis Optica Spectrum Disorder:A Retrospective, Cross-sectional Analysis
Neurol Neuroimmunol Neuroinflamm. 2022 Feb 25;9(3):e1147. doi: 10.1212/NXI.0000000000001147.PMID: 35217580
Benkert P, Meier S, Schaedelin S, Manouchehrinia A, Yaldizli Ö, Maceski A, Oechtering J, Achtnichts L, Conen D, Derfuss T, Lalive PH, Mueller C, Müller S, Naegelin Y, Oksenberg JR, Pot C, Salmen A, Willemse E, Kockum I, Blennow K, Zetterberg H, Gobbi C, Kappos L, Wiendl H, Berger K, Sormani MP, Granziera C, Piehl F, Leppert D, Kuhle J
Serum neurofilament light chain for individual prognostication of disease activity in people with multiple sclerosis: a retrospective modelling and validation study
NfL Reference Database in the Swiss Multiple Sclerosis Cohort Study Group.Lancet Neurol. 2022 Mar;21(3):246-257. doi: 10.1016/S1474-4422(22)00009-6.PMID: 35182510
Sari H, Galbusera R, Bonnier G, Lin Y, Alshelh Z, Torrado-Carvajal A, Mukerji SS, Ratai EM, Gandhi RT, Chu JT, Akeju O, Orhurhu V, Salvatore AN, Sherman J, Kwon DS, Walker B, Rosen B, Price JC, Pollak LE, Loggia M, Granziera C.
Multimodal Investigation of Neuroinflamation in Aviremic Patients With HIV on Antiretroviral Therapy and HIV Elite Controllers
Neurol Neuroimmunol Neuroinflamm. 2022 Feb 9;9(2):e1144. doi: 10.1212/NXI.0000000000001144. Print 2022 Mar. PMID: 35140142
Wendebourg MJ, Weigel M, Richter L, Gocheva V, Hafner P, Orsini AL, Crepulja V, Schmidt S, Huck A, Oechtering J, Blatow M, Haas T, Granziera C, Kappos L, Cattin P, Bieri O, Fischer D, Schlaeger R.
Spinal Cord Gray Matter Atrophy is associated with functional decline in Post-Polio Syndrome
Eur J Neurol. 2022 Feb 1. doi: 10.1111/ene.15261. PMID: 35102676
Giovannoni G, Popescu V, Wuerfel J, Hellwig K, Iacobeus E, Jensen MB, García-Domínguez JM, Sousa L, De Rossi N, Hupperts R, Fenu G, Bodini B, Kuusisto HM, Stankoff B, Lycke J, Airas L, Granziera C, Scalfari A.
Smouldering multiple sclerosis:the 'real MS'
Ther Adv Neurol Disord. 2022 Jan 25;15:17562864211066751. doi: 10.1177/17562864211066751. eCollection 2022.
Lokhande H, Rosso M, Tauhid S, Chu R, Healy BC, Saxena S, Barro C, Paul A, Polgar-Turcsanyi M, Anderson M, Glanz BI, Kropshofer H, Granziera C, Leppert D, Kappos L, Kuhle J, Weiner HL, Bakshi R, Chitnis T.
Serum NfL levels in the first five years predict 10-year thalamic fraction in patients with MS
Mult Scler J Exp Transl Clin. 2022 Jan 10;8(1):20552173211069348. doi: 10.1177/20552173211069348. eCollection 2022 Jan-Mar. PMID: 35035990
Sairanen V, Ocampo-Pineda M, Granziera C, Schiavi S, Daducci A.
Incorporating outlier information into diffusion-weighted MRI modelling for robust microstructural imaging and structural brain connectivity analyses
Neuroimage. 2022 Feb 15;247:118802. doi: 10.1016/j.neuroimage.2021.118802. Epub 2021 Dec 10. PMID: 34896584
Tsagkas C, Naegelin Y, Amann M, Papadopoulou A, Barro C, Chakravarty MM, Gaetano L, Wuerfel J, Kappos L, Kuhle J, Granziera C, Sprenger T, Magon S, Parmar K.
Central nervous system atrophy predicts future dynamics of disability progression in a real-world multiple sclerosis cohort
Eur J Neurol. 2021 Dec;28(12):4153-4166. doi: 10.1111/ene.15098. Epub 2021 Sep 17. PMID: 34487400
Schilling KG, Rheault F, Petit L, Hansen CB, Nath V, Yeh FC, Girard G, Barakovic M, Rafael-Patino J, Yu T, Fischi-Gomez E, Pizzolato M, Ocampo-Pineda M, Schiavi S, Canales-Rodríguez EJ, Daducci A, Granziera C, Innocenti G, Thiran JP, Mancini L, Wastling S, Cocozza S, Petracca M, Pontillo G, Mancini M, Vos SB, Vakharia VN, Duncan JS, Melero H, Manzanedo L, Sanz-Morales E, Peña-Melián Á, Calamante F, Attyé A, Cabeen RP, Korobova L, Toga AW, Vijayakumari AA, Parker D, Verma R, Radwan A, Sunaert S, Emsell L, De Luca A, Leemans A, Bajada CJ, Haroon H, Azadbakht H, Chamberland M, Genc S, Tax CMW, Yeh PH, Srikanchana R, Mcknight CD, Yang JY, Chen J, Kelly CE, Yeh CH, Cochereau J, Maller JJ, Welton T, Almairac F, Seunarine KK, Clark CA, Zhang F, Makris N, Golby A, Rathi Y, O'Donnell LJ, Xia Y, Aydogan DB, Shi Y, Fernandes FG, Raemaekers M, Warrington S, Michielse S, Ramírez-Manzanares A, Concha L, Aranda R, Meraz MR, Lerma-Usabiaga G, Roitman L, Fekonja LS, Calarco N, Joseph M, Nakua H, Voineskos AN, Karan P, Grenier G, Legarreta JH, Adluru N, Nair VA, Prabhakaran V, Alexander AL, Kamagata K, Saito Y, Uchida W, Andica C, Abe M, Bayrak RG, Wheeler-Kingshott CAMG, D'Angelo E, Palesi F, Savini G, Rolandi N, Guevara P, Houenou J, López-López N, Mangin JF, Poupon C, Román C, Vázquez A, Maffei C, Arantes M, Andrade JP, Silva SM, Calhoun VD, Caverzasi E, Sacco S, Lauricella M, Pestilli F, Bullock D, Zhan Y, Brignoni-Perez E, Lebel C, Reynolds JE, Nestrasil I, Labounek R, Lenglet C, Paulson A, Aulicka S, Heilbronner SR, Heuer K, Chandio BQ, Guaje J, Tang W, Garyfallidis E, Raja R, Anderson AW, Landman BA, Descoteaux M.
Tractography dissection variability:What happens when 42 groups dissect 14 white matter bundles on the same dataset?
Neuroimage. 2021 Nov;243:118502. doi: 10.1016/j.neuroimage.2021.118502. Epub 2021 Aug 22. PMID: 34433094
Weigel M, Dechent P, Galbusera R, Bahn E, Nair G, Lu PJ, Kappos L, Brück W, Stadelmann C, Granziera C.
Imaging multiple sclerosis pathology at 160 μm isotropic resolution by human whole-brain ex vivo magnetic resonance imaging at 3 T.
Sci Rep. 2021 Jul 29;11(1):15491. doi: 10.1038/s41598-021-94891-1. PMID: 34326420
Barakovic M, Girard G, Schiavi S, Romascano D, Descoteaux M, Granziera C, Jones DK, Innocenti GM, Thiran JP, Daducci A.
Bundle-Specific Axon Diameter Index as a New Contrast to Differentiate White Matter Tracts
Front Neurosci. 2021 Jun 15;15:646034. doi: 10.3389/fnins.2021.646034. eCollection 2021. PMID: 34211362
Maggi P, Kuhle J, Schädelin S, van der Meer F, Weigel M, Galbusera R, Mathias A, Lu PJ, Rahmanzadeh R, Benkert P, La Rosa F, Cuadra MB, Sati P, Théaudin M, Pot C, van Pesch V, Leppert D, Stadelmann C, Kappos L, Du Pasquier R, Reich DS, Absinta M, Granziera C.
Chronic White Matter Inflammation and Serum Neurofilament Levels in Multiple Sclerosis.
Neurology. 2021 Jun 4:10.1212/WNL.0000000000012326. DOI: 10.1212/WNL.0000000000012326. PMID: 34088875
Oechtering J, Schaedelin S, Benkert P, Müller S, Achtnichts L, Vehoff J, Disanto G, Findling O, Fischer-Barnicol B, Orleth A, Chan A, Pot C, Barakovic M, Rahmanzadeh R, Galbusera R, Heijnen I, Lalive PH, Wuerfel J, Subramaniam S, Aeschbacher S, Conen D, Naegelin Y, Maceski A, Meier S, Berger K, Wiendl H, Lincke T, Lieb J, Yaldizli Ö, Sinnecker T, Derfuss T, Regeniter A, Zecca C, Gobbi C, Kappos L, Granziera C, Leppert D, Kuhle J; Swiss Multiple Sclerosis Cohort Study.
Intrathecal Immunoglobulin M synthesis is an independent biomarker for higher disease activityand severity in multiple sclerosis.
Ann Neurol. 2021 May 31. doi: 10.1002/ana.26137.
Cristina Granziera, Jens Wuerfel, Frederik Barkhof, Massimiliano Calabrese, Nicola De Stefano, Christian Enzinger, Nikos Evangelou, Massimo Filippi, Jeroen J.G. Geurt, Daniel S. Reich, Maria A. Rocca, Stefan Ropele, Àlex Rovira, Pascal Sati, Ahmed T. Toosy, Hugo Vrenken, Claudia A. M. Gandini Wheeler-Kingshott and Ludwig Kappos on behalf of the MAGNIMS Study Group*
Quantitative magnetic resonance imaging towards clinical application in multiple sclerosis
Brain, 2021 May 10
Lu P.J., Barakovic M., Weigel M., Rahmanzadeh R., Galbusera R., Schiavi S., Daducci A., La Rosa F., Bach Cuadra M., Sandkühler S., Kuhle J., Kappos L., Cattin P., Granziera C.
GAMER-MRI in Multiple Sclerosis identifies the diffusion-based micro-structural measures that are most sensitive to focal damage: a deep-learning based-analysis and clinico-biological validation
Frontiers in Neuroscience, 2021 April 6
Rahmanzadeh Reza, Lu Po-Jui, Barakovic Muhamed, Weigel Matthias, Maggi Pietro, Nguyen Than D., Schiavi Simona, Daducci Alessandro, La Rosa Francesco, Schaedelin Sabine, Absinta Martina, Reich Daniel S., Sati Pascal, Wang Yi, Cuadra Merixtell Bach, Radue Ernst-Wilhelm, Kuhle Jens, Kappos Ludwig, Granziera Cristina
Myelin and axon pathology in multiple sclerosis assessed by myelin water and multi-shell diffusion imaging
Brain. 2021 Mar 9
Po-Jui, Youngjin Yoo, Reza Rahmanzadeh, Riccardo Galbusera, Matthias Weigel, Pascal Ceccaldi, Thanh D. Nguyen, Pascal Spincemaille, Yi Wang, Alessandro Daducci, Francesco La Rosa, Meritxell Bach Cuadra, Robin Sandkuehler, Kambiz Nael, Amish Doshi, Zahi A. Fayad, Jens Kuhle, Ludwig Kappos, Benjamin Odry, Philippe Cattin, Eli Gibson, Cristina Granziera
GAMER MRI: Gated-Attention mechanism ranking of multi-contrast MRI in brain pathology
Neuroimage Clin. 2021;29:102522.
La Rosa F., Abdulkadir A., Fartaria M.J., Rahmanzadeh R., Lu P.J., Galbusera R., Barakovic M., Thiran J.P., Granziera C., Bach Cuadra M..
Multiple sclerosis cortical and WM lesion segmentation at 3T MRI: a deep learning method based on FLAIR and MP2RAGE.
NeuroImage. Clinical, 27 p. 102335, 2020/06/30.
Todea R-A., Lu P.-J., Fartaria J., Bonnier G., Du Pasquier R., Krueger G., Bach Cuadra M., Psychogios M, Kappos L., Kuhle J., Granziera C.
Evolution of cortical and white matter lesion load in early-stage multiple sclerosis: correlation with neuroaxonal damage and clinical changes.
Front Neurol. 2020 Sep 4;11:973
Fartaria Mário João, Roche Alexis, Meuli Reto, Granziera Cristina, Kober Tobias, Bach Cuadra Meritxell.
Segmentation of Cortical and Subcortical Multiple Sclerosis Lesions Based on Constrained Partial Volume Modeling.
pp. 142-149 dans Lecture Notes in Computer Science, Springer International Publishing, 2017.
Pizzorni Ferrarese F., Daducci A., Bach Cuadra M., Lemkaddem A., Granziera C., Thiran J.P., Menegaz G..
Towards a diffusion image processing validation and accuracy prediction framework.
pp. 2269-2272 dans ICIP 2011, 18th IEEE International Conference on Image Processing, Proceedings of the International Conference on Image Processing, 2011.